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Anti-Depressants Cause Autism in Fetuses
3 weeks ago
General
This is a work of fiction. Names, characters, businesses, places, events and incidents are either the products of the author’s imagination or used in a fictitious manner. Any resemblance to actual persons, living or dead, or actual events is purely coincidental.
Is psychiatry committing mass soft-abortions? They do have a history of committing chemical castration and chemical lobotomies. Now they're chemically castrating your children yet unborn.
Prenatal SSRI Exposure Increases the Risk of Autism in Rodents via Aggravated Oxidative Stress and Neurochemical Changes in the Brain
https://pmc.ncbi.nlm.nih.gov/articles/PMC9963091/ - 2023 Feb 20
Abstract
The mechanisms underlying selective serotonin reuptake inhibitor (SSRI) use during pregnancy as a major autism risk factor are unclear. Here, brain neurochemical changes following fluoxetine exposure and in an autism model were compared to determine the effects on autism risk. The study was performed on neonatal male western albino rats which were divided into Groups one (control), two (propionic acid [PPA]-induced autism model), and three (prenatal SSRI-exposed newborn rats whose mothers were exposed to 5 mg/kg of fluoxetine over gestation days 10–20). SSRI (fluoxetine) induced significant neurochemical abnormalities in the rat brain by increasing lipid peroxide (MDA), Interferon-gamma (IFN-γ), and caspase-3 levels and by depleting Glutathione (GSH), Glutathione S-transferases (GST), Catalase, potassium (K+), and Creatine kinase (CK) levels, similarly to what has been discovered in the PPA model of autism when compared with control. Prenatal fluoxetine exposure plays a significant role in asset brain damage in newborns; further investigation of fluoxetine as an autism risk factor is thus warranted.
Introduction
Many studies have reported the associations of prenatal depression with the brain development of infants. Depression during pregnancy is a major health issue not only for mothers but also for newborns. Children of depressed females during pregnancy are four times more likely to be diagnosed with depression in their teenage years than those unexposed to antenatal depression. Maternal anxiety in pregnancy is associated with lower mental development scores, hyperactivity, and behavioral and emotional problems in children. Most women use antidepressants during pregnancy as they experience depression and anxiety disorders in their reproductive years [9]. SSRIs are among the most prescribed medications for maternal depression as it mainly targets the serotoninergic system [10]. SSRIs can pass the human placenta to reach the fetus, and they can also be consumed by neonates through nursing because their active metabolites are excreted into human milk [11]. Many studies have reported neurological issues and other health problems in children exposed to SSRIs before birth. Recently, Zengeler et al. [12] reported a strong inflammatory reaction at the maternal–fetal interface due to SSRI treatment during pregnancy. Babies that are exposed to inflammation develop behavioral changes such as diminished communication and decreased interest in social interactions. An immune challenge during pregnancy can lead to permanent brain changes [12].
Prenatal SSRI Exposure Increases the Risk of Autism in Rodents via Aggravated Oxidative Stress and Neurochemical Changes in the Brain
https://pmc.ncbi.nlm.nih.gov/articles/PMC9963091/ - 2023 Feb 20
Abstract
The mechanisms underlying selective serotonin reuptake inhibitor (SSRI) use during pregnancy as a major autism risk factor are unclear. Here, brain neurochemical changes following fluoxetine exposure and in an autism model were compared to determine the effects on autism risk. The study was performed on neonatal male western albino rats which were divided into Groups one (control), two (propionic acid [PPA]-induced autism model), and three (prenatal SSRI-exposed newborn rats whose mothers were exposed to 5 mg/kg of fluoxetine over gestation days 10–20). SSRI (fluoxetine) induced significant neurochemical abnormalities in the rat brain by increasing lipid peroxide (MDA), Interferon-gamma (IFN-γ), and caspase-3 levels and by depleting Glutathione (GSH), Glutathione S-transferases (GST), Catalase, potassium (K+), and Creatine kinase (CK) levels, similarly to what has been discovered in the PPA model of autism when compared with control. Prenatal fluoxetine exposure plays a significant role in asset brain damage in newborns; further investigation of fluoxetine as an autism risk factor is thus warranted.
Introduction
Many studies have reported the associations of prenatal depression with the brain development of infants. Depression during pregnancy is a major health issue not only for mothers but also for newborns. Children of depressed females during pregnancy are four times more likely to be diagnosed with depression in their teenage years than those unexposed to antenatal depression. Maternal anxiety in pregnancy is associated with lower mental development scores, hyperactivity, and behavioral and emotional problems in children. Most women use antidepressants during pregnancy as they experience depression and anxiety disorders in their reproductive years [9]. SSRIs are among the most prescribed medications for maternal depression as it mainly targets the serotoninergic system [10]. SSRIs can pass the human placenta to reach the fetus, and they can also be consumed by neonates through nursing because their active metabolites are excreted into human milk [11]. Many studies have reported neurological issues and other health problems in children exposed to SSRIs before birth. Recently, Zengeler et al. [12] reported a strong inflammatory reaction at the maternal–fetal interface due to SSRI treatment during pregnancy. Babies that are exposed to inflammation develop behavioral changes such as diminished communication and decreased interest in social interactions. An immune challenge during pregnancy can lead to permanent brain changes [12].
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