Well she's throwing knives at the caster, just like a veteran D&D player. Will the spell collapse? Is the caster dead?

Fortunately, she's got more than a single 1d4 hit die.

Hum, this is looking bad, but since its ruins magic, I do not think it's dependent on the caster, it probably has a life of its own once started, and me thinks that Leilani is coming out of Lorelei vessels, like it or not. Wondering what this will do to Sisari when that happens. On the other hand, Endimion will probably end her life stream before that expelling Sisari which I believe we were explained that once without a vessel while outside the dragon’s realm she will be automatically return to the dragon realm as a blank slate, and my guess is that the ruins will finally bring Leilani back and she will bring Loreli back to the living having not die for long enough to be taken away from her body and heel Callie...