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Danielle was working in her lab late on night when her eyes beheld an eerie sight a spider in her DNA splicer, unfortunately she had already started the process!
Fusing spider with several other samples, resulting in horrifying hybrid beasts!
Sheep, Cows, Polar bear, and even an Elephant! They grew fast in the tubes, much faster than she could've managed to stop even if she wanted too. They were soon full grown adults, ready to be unleashed on the world.
Danielle: "Oh fluff no! No NO NO NO NO! What have I done!?"
The cat said in a panic as the eyes of the various monsters opened. Would they be friendly? Would they be vicious? Would they try to devour her and everyone she loves, plunging the town into chaos eating everyone in sight?
The scientist was about to find out one way or the other as the elephant burst forth from her enclosure, six mighty if somewhat chubby arms reaching for her.
The tiny cat trying to make a run for it, soon getting cornered by the pair of cows, making sure she didn't get away. The polar bear grabbing her by the tail and hoisting her up, with a hungry look in her four shining eyes. The elephant being the slowest she wrapped her trunk around the little scientist and bringing her to her maw, licking her lips. Her hot breath streaking across her creator's face, Danielle terrified beyond words, too frightened to scream for help. The elephant's tongue licking up the side of her face like a scared lollipop. Perhaps about to bite down... When suddenly her step-sister Stephanie burst in the door!
Stephanie: "Put her down!!" As she rushed at the monsters in the room disregarding her own safety, getting scooped up by the polar bear before she could make any progress.
Polar bear: "Nice doggy, you look like a good toy for us to play with.."
Danielle: "YOU CAN TALK?!!?!"
Elephant: "Yeah? You thought we couldn't?" The cows then chimed in and said: "Cute dog, maybe her and the cat will be fun!"
Danielle: "Please let us go! I-I'll do whatever you want just please I beg of you don't kill us!!"
Elephant: "Kill you? No no no, we have better plans for you. Don't we girls?" The monsters each got a sick and seductive looks in their quad eyes. Danielle: "Steph, if we don't make it out of this.. I've always loved you sis." Stephanie: "L-love you to sis!"

After about four hours of some of the raunchiest, depraved, lust ridden things your warped mind can imagine the monsters were lying around satisfied from it all. Stephanie still flailing with her legs poking out from the elephant's ass cheeks having been used as a love toy by the monstrosity. Soon managing to work herself free of her grasp.
Stephanie: "Ewww, I like a big butt as much as the next gal but even I have my fluffing limits. Dani? DANI? DANI!?!?!"

*meow*

Danielle called out from the polar bear's throat, having been half-swallowed. Not with the intention of eating her, just savoring her taste. Stephanie pulled her out and the two made a break for it as fast as they could make it.

Stephanie: "Do I even want to know why the frick you made those things? I get that you are lonely but that was ridiculous!"
Danielle: "Those were an accident! I swear! Those whatever they weren't intentional!"
Stephanie: "Right, they didn't lay eggs or some crap in our wombs did they?"
Danielle: "Probably not, all my genetic experiments are sterile. Like the ones in those dinosaur movies."
Stephanie: "Should we burn the lab down?"
Danielle: "Absolutely not! I've got years worth of research in there! Maybe we can find a use for those creatures?"
As she hobbled off, sore from the excessive mating habits of the hybrid monsters.