Yes, a VERY big size difference ( ͡° ͜ʖ ͡°)

If Neferu is really that concerned about the size difference between Marco and Amicus, then I wonder if he feels that he could be a much better and safer choice for the human in the sense of being his partner or companion for the rest of the human(s) stay on the moon, especially in the case of the distinction in sizes in between each other with his Anubin jackal anatomy/physiology right up alongside Macro’s human body which might as well as include whether they could work around all the pros and cons that they might find out about each other (while being physically intimate, as well as exploring, each other’s pleasures as well as their bodies limitations) only if they happen to plan to take up a serious relationship with each other either during when they first meet each other or much later on as they stay together for their long unintentional visit on that moon known Adastra, or maybe even possibly they would be willing to share their love/lust between each other with Amicus as well only if that’s an option that the wolf prince would consider to take them up on especially if it’s an arrangement for all of them to be so intimate and close to each other like that at all that is (specially, in particular if it all happens right before or after they found themselves in their current predicament because of Marco‘s current situation caused mainly due to Amicus’s ignorant actions of course) (!/?).